Our data demonstrate that the discontinuation of 5ARIs during combination therapy induces prostate regrowth, as well as aggravation of symptoms in men with BPH. This result, therefore, suggests that the life-long use of 5ARIs should be considered for the prevention of BPH progression.

http://beta.docguide.com/effect-discontinuation-5alpha-reductase-inhibitors-prostate-volume-and-symptoms-men-bph-prospective-?hash=be5c783b&eid=4200